800mg CBN-Rich Tincture | Natural Sleep Support | Zero THC

The Sleep Cannabinoid. Scientifically Formulated for Rest.

Cannabinol (CBN) is a partial CB1 receptor agonist — a pharmacological profile that distinguishes it from CBD and positions it as the most sleep-relevant cannabinoid in the broad spectrum profile. While CBD is associated with broad ECS modulation and CBG with energy and focus, CBN's CB1 partial agonism produces sedative and calming effects that make it the targeted choice for sleep onset and nighttime relaxation.

cbdDR's 800mg CBN-Rich Tincture delivers 650mg CBN as the primary active cannabinoid per bottle — a concentration that makes CBN the dominant therapeutic agent, not a trace element. Formulated in-house by botanical scientist Matthew Scott since 2014. Standardized. Third-party tested every batch.

Formulation Specifications

• Total Cannabinoids: 800mg per 30ml bottle
• Primary Cannabinoid: CBN (Cannabinol) — 650mg
• Supporting Cannabinoids: CBD — 50mg | CBC — 50mg | CBG — 50mg
• Serving Size: 1ml sublingual
• Servings Per Bottle: ~30
• Cannabinoids Per Serving: ~27mg
• THC: Zero — non-detected on every batch COA
• Carrier: MCT Oil (coconut-derived)
• Administration: Sublingual (under tongue, hold 60–90 seconds)

How CBN Works: The Science

• CB1 receptor partial agonism — CBN binds to CB1 receptors in the brain and nervous system with moderate affinity (higher than CBD, lower than THC), producing sedative and calming effects without psychoactive intoxication
• TRPV2 receptor interaction — CBN interacts with TRPV2 channels involved in pain modulation, which may indirectly support sleep quality in individuals with pain-disrupted sleep
• Entourage synergy — CBN's sedative effects may be amplified in the presence of other cannabinoids, particularly the CBC (50mg) in this formulation which contributes anandamide reuptake inhibition for additional calming support

A 2021 review by Corroon in Medical Cannabis and Cannabinoids examined available CBN research and noted its sedative-relevant mechanisms, while acknowledging the need for rigorous human clinical trials. cbdDR presents this evidence honestly — CBN's mechanisms are scientifically plausible for sleep support, and human clinical data continues to develop.

CBN vs. Melatonin: A Different Mechanism

Melatonin regulates circadian rhythm timing via MT1/MT2 receptors — it shifts when you sleep. CBN works through CB1 receptor partial agonism — it supports the quality and onset of sleep through endocannabinoid system modulation. These are complementary, not competing mechanisms. CBN may be particularly appropriate for those who don't respond to melatonin or who experience sleep disruption from stress, anxiety, or pain rather than circadian misalignment.

Suggested Use

Place 1ml under tongue using the dropper. Hold for 60–90 seconds. Swallow. Take 30–60 minutes before desired sleep time. Consistent nightly use for 2–4 weeks is recommended to assess full effect as the endocannabinoid system responds to regular cannabinoid input.

Third-Party Testing

Every batch tested by an ISO/IEC 17025-accredited independent laboratory. Full-panel COA: potency, heavy metals, pesticides, residual solvents, microbials. Results published batch-by-batch in our Batch Database.

Quality Assurance

• ✅ 650mg CBN primary — standardized, not trace amounts
• ✅ Formulated in-house by Matthew Scott, Botanical Scientist
• ✅ Zero THC — verified by independent laboratory testing
• ✅ ISO/IEC 17025-accredited third-party testing every batch
• ✅ No white label — every formulation is our own

View Batch Database →  |  CBN Science Page →  |  CBN & Sleep Science Article →  |  CBN vs. Melatonin →

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare provider before use.